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Brain enzyme caught in the act

  • January 5, 2021

Researchers from the lab of Wim Versées (VIB-VUB Center for Structural Biology) in collaboration with the team of Patrik Verstreken (VIB-KU Leuven Center for Brain & Disease Research) presents the three-dimensional structure of an enzyme involved in Parkinson’s disease, epilepsy, Alzheimer's disease, and Down syndrome. Enzymes are a class of proteins that speed up biological processes in our body, including our brain. That is why 'errors' in these enzymes often lead to devastating neurological diseases. The new structure shows the enzyme 'in action' and opens the door for new smart drug development strategies.

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